BRISTLE - Oral Health for Longevity
Hello again 👋 This is MYKIGAI’s Curation for Longevity 🧬🛍 by Laura Minquini. We are a discovery and recommendation platform for longevity.
Our Longevity ToolKits are prepared by our Geroscientist, Girish Harinath.
We will continue our Who is Who in Longevity this Saturday! We are interrupting that as we are going to start publishing our Longevity Drops on Wednesdays. Look out for them! 👀
This week’s drop is particularly important as oral health is so undermined and yet so crucial for longevity. Let’s find out more!
BRISTLE
Tagline: Stop guessing and start measuring your oral health.
Mission: “Our vision is a new kind of care that prioritizes preventing disease instead of reactively treating it - oral health made for you, delivered to you, and owned by you.”
Why we think they are a longevity brand: Their mission is rooted in preventive health which is aligned with everything we think is important to age healthier. Did you know that periodontal disease is a common inflammatory disease affecting up to 50% of the adult population? As Bristle stated on their site: “Our mouths are gateways to the rest of our bodies—so oral health plays a large role in reducing our risk for other diseases.” Think cancer, cognitive decline and heart disease prevention via your mouth.
All my serious longevity enthusiasts friends - the type that takes 30 supplements a day and tests non-prescribed drugs like Rapamycin - floss their teeth multiple times a day. Your oral health unlocks longevity.
Notable: The team are alumni of Y Combinator, companies like Airbnb came out of this prestigious startup accelerator, so they are just getting started.
What do they do?
Bristle created a saliva test to measure your levels of oral bacteria that cause cavities, bad breath, gum disease, etc.
They use genomics to measure the good and harmful bacteria in your saliva.
Two parts to the product - test and report, the report provides insights and recommendations based on the test data.
The test provides early detection of risk factors for oral diseases.
Saliva test screens the oral microbiome.
The science behind their product
Some of the microbes in our body are helpful, some are harmful. A microbiome screening via Bristle detects and identifies them.
The oral microbiome contains trillions of bacteria, viruses, and fungi.
With genomics, they analyze DNA in every microbe found in the saliva test to detect which species are present and in what quantity.
Functions of helpful mouth bacteria:
Digesting food
Stimulating saliva
Maintaining oral health
Consequences of harmful mouth bacteria:
Tooth decay and cavities
Gum disease
Bad breath
Downstream effects of poor oral health:
Damaged salivary glands
Cardiovascular disease and diabetes
High levels of bacteria, which can be correlated/cause bodily diseases
Their algorithm matches the unique risk profile with recommendations to optimize your health.
Diet, hygiene, and other factors impact and influence your oral microbiome
Most oral diseases are caused by an abundance of harmful microbes.
Overall health outcomes that are impacted by oral hygiene → Alzheimer’s disease, cardiovascular disease, adverse pregnancy outcomes, diabetes, gastrointestinal diseases, respiratory conditions.
Snapshot
Learn more about how oral bacteria affect our body from Bristle’s co-founder, Brian Maurer.
Bristle Team
You can learn more about the team and advisers here.
Why does this innovation matters to you?
There are links between oral microbiomes and your risk of cognitive decline, heart disease, and cancer -> oral microbiome can influence your overall health outside of your mouth, it is super important to maintain but most people are relatively unaware of its significance.
Detecting oral health problems at an early stage is less costly overall. Late-stage detection results in expensive procedures like root canals and filling cavity fillings.
Read more about this on our Oral Hygiene Protocol below.
Must read from Bristle
🎧 Listen to our Let’s Talk Longevity Podcast
We got to interview one of Bristle’s co-founders Danny Grannick.
Some highlights:
Differences between pathogenic and non-pathogenic bacteria
Danny’s Oral Hygiene Protocol
The truth about mouthwash
Good oral health benefits and statistics on how they improve health outcomes
INTERVIEW 🎙 HERE
Price Point:
A one-time purchase is $119
Subscribe & Save from $99 per test:
4 tests per year One test shipped every 3 months is $99 per test
2 tests per year One test shipped every 6 months is $109 per test
For now, it ships only to the US.
🎯 Listen to our podcast to learn more about frequency by age.
🚨 MYKIGAI Subscribers Alert
👉🏼 Enjoy 15% off with the code MYKIGAI
Access our Oral Hygiene Protocol below 👇🏼
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